Metodología para el desarrollo de los estudios de seguridad toxicológica de metabolitos secundarios extraídos de Agave brittoniana Trel. spp. Brachypus con fines cosmecéuticos
Fecha
2021
Autores
Castillo Muguruza, Yanielis
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Editor
Universidad Central ¨Marta Abreu¨ de Las Villas. Facultad de Química y Farmacia. Departamento de Farmacia
Resumen
Desde su surgimiento, a mediados de la década de los 90, los cosmecéuticos irrumpieron con fuerza en el mercado de la estética profesional, lejos de convertirse en una moda pasajera, constituyen, según los analistas, el sector con mayor potencial de crecimiento de la industria cosmética. Sin embargo, pocos de estos productos están avalados por estudios de seguridad toxicológica. Por tal motivo esta investigación tiene como objetivo diseñar una metodología para el desarrollo de los estudios de seguridad toxicológica de metabolitos secundarios extraídos de Agave brittoniana Trel. spp. Brachypus con fines cosmecéuticos. Para el desarrollo de la investigación se analizan procedimientos normativos y documentos regulatorios para el registro de productos cosmecéuticos en Cuba, además, procedimientos normativos que rigen los estudios toxicológicos para comprobar la seguridad de los productos y, se establece la metodología para el desarrollo de los estudios de seguridad toxicológica de metabolitos secundarios extraídos de Agave brittoniana. Como resultados de la investigación se comprobó que los procedimientos normativos y registros analizados carecen de regulaciones para productos cosmecéuticos en Cuba y se confeccionó la metodología para el desarrollo de los estudios seguridad toxicológica de metabolitos secundarios extraídos de Agave brittoniana Trel. spp. Brachypus con fines cosmecéuticos.
Palabras claves: Cosmecéuticos, seguridad toxicológica, Agave brittoniana Trel. regulaciones.
Since their emergence, in the mid-90s, cosmeceuticals broke into the professional aesthetics market with force, far from becoming a fad, they constitute, according to analysts, the sector with the highest growth potential in the cosmetic industry. However, few of these products are supported by toxicological safety studies. For this reason, this research aims to design a methodology for the development of toxicological safety studies of secondary metabolites extracted from Agave brittoniana Trel. spp. Brachypus for cosmeceutical purposes. For the development of the research, normative procedures and regulatory documents for the registration of cosmeceutical products in Cuba are analyzed, in addition, normative procedures that govern toxicological studies to verify the safety of the products and, it is established the methodology for the development of the studies of toxicological safety of secondary metabolites extracted from Agave brittoniana. As results of the investigation, it was found that the normative procedures and analyzed registries lack regulations for cosmeceutical products in Cuba and the methodology for the development of toxicological safety studies of secondary metabolites extracted from Agave brittoniana Trel. spp. Brachypus was drawn up for cosmeceutical purposes. Keywords: Cosmeceuticals, toxicological safety, Agave brittoniana Trel. spp. Brachypus, regulations.
Since their emergence, in the mid-90s, cosmeceuticals broke into the professional aesthetics market with force, far from becoming a fad, they constitute, according to analysts, the sector with the highest growth potential in the cosmetic industry. However, few of these products are supported by toxicological safety studies. For this reason, this research aims to design a methodology for the development of toxicological safety studies of secondary metabolites extracted from Agave brittoniana Trel. spp. Brachypus for cosmeceutical purposes. For the development of the research, normative procedures and regulatory documents for the registration of cosmeceutical products in Cuba are analyzed, in addition, normative procedures that govern toxicological studies to verify the safety of the products and, it is established the methodology for the development of the studies of toxicological safety of secondary metabolites extracted from Agave brittoniana. As results of the investigation, it was found that the normative procedures and analyzed registries lack regulations for cosmeceutical products in Cuba and the methodology for the development of toxicological safety studies of secondary metabolites extracted from Agave brittoniana Trel. spp. Brachypus was drawn up for cosmeceutical purposes. Keywords: Cosmeceuticals, toxicological safety, Agave brittoniana Trel. spp. Brachypus, regulations.
Descripción
Palabras clave
Cosmecéuticos, Industria Cosmética, Agave brittoniana Trel. spp. Brachypus, Seguridad Toxicológica